HCID 66841437, compound → HCID 59600217, compound

HRID 1929205Notes

Reaction equation

HRID 1929205 reaction equation
OC1C(O)CCN(C(C)[CH2:10][N:11]2[CH2:16][CH2:15][CH:14]([NH:17][C:18]([C:20]3[NH:21][C:22]4[C:27]([CH:28]=3)=[C:26]([O:29][CH2:30][C:31]3[C:35]5[CH:36]=[C:37]([Cl:40])[CH:38]=[CH:39][C:34]=5[O:33][CH:32]=3)[CH:25]=[CH:24][CH:23]=4)=[O:19])[CH2:13][CH2:12]2)C1.[CH2:42]1[CH:47]2C(CO)[CH2:49][CH2:50][CH2:51][N:46]2[CH2:45][CH2:44][O:43]1>>[CH2:42]1[C@@H:47]2[C@H:49]([CH2:10][N:11]3[CH2:12][CH2:13][CH:14]([NH:17][C:18]([C:20]4[NH:21][C:22]5[C:27]([CH:28]=4)=[C:26]([O:29][CH2:30][C:31]4[C:35]6[CH:36]=[C:37]([Cl:40])[CH:38]=[CH:39][C:34]=6[O:33][CH:32]=4)[CH:25]=[CH:24][CH:23]=5)=[O:19])[CH2:15][CH2:16]3)[CH2:50][CH2:51][N:46]2[CH2:45][CH2:44][O:43]1

Participants

3

Reactant 2

HCID 66841437HCID 66841437, compoundHCID 66841441HCID 66841441, compound

Product 1

HCID 59600217HCID 59600217, compound

Procedure

This compound is synthesized from the compound 176 (see example 138) and (9RS,9aSR)-1-(octahydro-pyrido[2,1-c][1,4]oxazin-9-yl)-methanol (67) analogously to the method described in example 127.

Sources & evidence

ORD record
ord-fb0c816a0ec64f6a9642903fec414d37
Source dataset
uspto-grants-2012_05
Patent number
US08183366B2

Reaction notes

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