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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929212Generated: November 1, 2026

3-Methyl-4-piperidyl (3S,4S)-Pivalate → HCID 59600158, compound

https://huagongshe.com/reaction/1929212

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-piperidyl (3S,4S)-PivalateHCID 59600241—
ReactantHCID 66841736HCID 66841736—
ProductHCID 59600158HCID 59600158—

Reaction Steps

This compound is synthesized from 4-(6-Methoxy-pyridin-3-yl)-1H-indole-2-carboxylic acid [1-(2-hydroxy-ethyl)-piperidin-4-yl]-amide (184, preparation see below) and 2,2-Dimethyl-propionic acid (3S,4S)-3-methyl-piperidin-4-yl ester (17) analogously to the method described in example 150, followed by cleavage of the protecting group.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183366B2
Source datasetuspto-grants-2012_05
ORD IDord-bc1e9b5bcf7d49e6a0c835c6828393ac
Source noteuspto-grants-2012_05