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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929219Generated: November 1, 2026

Azepan-4-ol → 4-Isobutoxy-1H-indole-2-carboxylic acid {1-[2-(4-hydroxy-azepan-1-yl)-ethyl]-piperidin-4-yl}-amide

https://huagongshe.com/reaction/1929219

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAzepan-4-olHCID 5149746—
Reactant4-Isobutoxy-1H-indole-2-carboxylic acid [1-(2-hydroxy-ethyl)-piperidin-4-yl]-amideHCID 66841627—
Product4-Isobutoxy-1H-indole-2-carboxylic acid {1-[2-(4-hydroxy-azepan-1-yl)-ethyl]-piperidin-4-yl}-amideHCID 58916322—

Reaction Steps

This compound is synthesized analogously to example 150 from 4-isobutoxy-1H-indole-2-carboxylic acid [1-(2-hydroxy-ethyl)piperidin-4-yl]-amide, 190 and azepan-4-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183366B2
Source datasetuspto-grants-2012_05
ORD IDord-afee250e58494128af919fea033ccdf5
Source noteuspto-grants-2012_05