HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azepan-3-amine → 4-Isobutoxy-1H-indole-2-carboxylic acid {1-[2-(3-amino-azepan-1-yl)-ethyl]-piperidin-4-yl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azepan-3-amine | HCID 2756445 | — |
| Reactant | 4-Isobutoxy-1H-indole-2-carboxylic acid [1-(2-hydroxy-ethyl)-piperidin-4-yl]-amide | HCID 66841627 | — |
| Product | 4-Isobutoxy-1H-indole-2-carboxylic acid {1-[2-(3-amino-azepan-1-yl)-ethyl]-piperidin-4-yl}-amide | HCID 58916323 | — |
Reaction Steps
This compound is synthesized analogously to example 150 from 4-isobutoxy-1H-indole-2-carboxylic acid [1-(2-hydroxy-ethyl)piperidin-4-yl]-amide, 190 and azepan-3-ylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183366B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-485ce0e07ca349b3984631e12632eb88 |
| Source note | uspto-grants-2012_05 |