HCID 86646932, compound → HCID 68512324, compound

Participants

Reaction Steps

In an autoclave, cover 36 mg of platinum oxide with 5 cm3 of ethanol; add a solution of 600 mg of 4-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-1,2-dinitrobenzene in 67 cm3 of ethanol. This mixture is hydrogenated under 200 kPa of hydrogen and at a temperature close to 20° C. After reaction for about twenty hours, the mixture is filtered and concentrated under vacuum under reduced pressure (0.2 kPa). After filtration on silica [eluent: dichloromethane/methanol (98/2 by volume)], we obtain 316 mg of 4-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]benzene-1,2-diamine in the form of a brown resin, which has the following characteristics:

Provenance & Evidence