(1-Bromoethyl)benzene → Benzo(d)thiazol-2-amine

Participants

Reaction Steps

6-(1-Phenylethoxy)-1,3-benzothiazol-2-amine can be prepared as in Example 8 but from 0.5 g of 2-amino-1,3-benzothiazol-6-ol and 0.555 g of (1-bromoethyl)benzene. After purification of the residue by silica-column flash chromatography [eluent: dichloromethane/methanol (95/5 by volume)], we obtain 0.308 g of 641-phenylethoxy)-1,3-benzothiazol-2-amine in the form of a thick brown oil, which has the following characteristics:

Provenance & Evidence