HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 5-Fluoro-6-[1-(2,3,6-trichlorophenyl)ethoxy]-1,3-benzothiazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Potassium thiocyanate | HCID 516872 | — |
| Reactant | 3-Fluoro-4-[1-(2,3,6-trichlorophenyl)ethoxy]aniline | HCID 68512300 | — |
| Product | 5-Fluoro-6-[1-(2,3,6-trichlorophenyl)ethoxy]-1,3-benzothiazol-2-amine | HCID 86646950 | 74.7% |
Reaction Steps
5-Fluoro-6-[1-(2,3,6-trichlorophenyl)ethoxy]-1,3-benzothiazol-2-amine was prepared according to the method described in Example 20d but from 1.35 g of 3-fluoro-4-[1-(2,3,6-trichlorophenyl)ethoxy]aniline, 1.56 g of potassium thiocyanate and 0.207 cm3 of dibromine. We obtain 1.18 g of 5-fluoro-6-[1-(2,3,6-trichlorophenyl)ethoxy]-1,3-benzothiazol-2-amine in the form of an orange-coloured powder, which has the following characteristics:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188078B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-e92a7830fd134fb79855e2ff53766e50 |
| Source note | uspto-grants-2012_05 |