HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 57474985, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Bromomethyl tricyclo[3.3.1.13,7]dec-1-yl ketone | HCID 197820 | — |
| Reactant | Ethyl 4-(piperazin-1-yl)benzoate | HCID 2761178 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 57474985 | HCID 57474985 | — |
Reaction Steps
Ethyl 4-(piperazin-1-yl)benzoate (100 mg), 1-admantyl bromomethyl ketone (110 mg) and sodium carbonate (46 mg) were suspended in anhydrous acetonitrile (2 mL). The reaction mixture was stirred at room temperature overnight. The reaction was quenched with saturated NaHCO3 aqueous solution, and extracted with ethyl acetate. The organic phase was washed with water, brine, dried over Na2SO4, filtered and concentrated to afford the title compound
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188077B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-949190de74c5433081d0f1bb9d393357 |
| Source note | uspto-grants-2012_05 |