反应详情

In analogy to step c) in the synthesis of Building block I, the reaction of (R)-5-(5-bromo-2-fluoro-phenyl)-5-methyl-5,6-dihydro-2H-[1,4]oxazin-3-ylamine with 4,4′-dimethoxytriphenylmethyl chloride yielded the title compound as a white solid (72% of theory). Mass (calculated) C32H30BrFN2O3 [589.51]; (found) [M+H]+=589, [M+2-H]+=591.

1. customIn analogy to step c) in the synthesis of Building block I