HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 57431049, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrate;hydrochloride | HCID 21885828 | — |
| Reactant | HCID 86632296 | HCID 86632296 | — |
| Solvent | Water ethylacetate | HCID 22728543 | — |
| Product | HCID 57431049 | HCID 57431049 | — |
Reaction Steps
A solution of Example 1, A2 (1 eq) in AcOH:conc.HCl:H2O (1:10:1, 0.065 M) was heated at reflux overnight. The reaction mixture was then cooled down to RT and diluted with water/EtOAc. The organic phase was washed with brine, dried (Na2SO4), and concentrated under reduced pressure. MS (ES) C14H12ClFN2O2 required: 294/296. found: 295/297 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188084B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-d3416be5c3644bcf8a5bf09fbe36a76f |
| Source note | uspto-grants-2012_05 |