2-Chlorobenzaldehyde → HCID 25027763, compound

Participants

Reaction Steps

The method of Example 3 was used, wherein 3-pyridinecarboxamidine hydrochloride and 2-chloro-4-fluorobenzaldehyde were separately replaced by 2-amidinopyrazinium hydrochloride and 2-chlorobenzaldehyde to obtain a yellow solid of 0.21 g (yield 29%); 1H-NMR (400 MHz, CDCl3) δ 2.15-2.19 (2H, m, CH2); 2.45-2.85 (4H, s, CH2); 6.19 (1H, s, CH); 7.13-7.40 (4H, m, ArH); 8.27 (1H, s, ArH); 8.51 (H, m, ArH); 8.69 (H, m, ArH); 9.57 (1H, s, NH). MS (EI) 338.2 (M+).

Provenance & Evidence