HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,4-Dimethyl-1H-imidazol-1-yl)ethanamine → 1,3-Dimethyl-8-[2-(4-trifluoromethyl-phenyl)-ethyl]-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,4-Dimethyl-1H-imidazol-1-yl)ethanamine | HCID 18460700 | — |
| Reactant | 3-[4-(Trifluoromethyl)phenyl]propanal | HCID 21683807 | — |
| Product | 1,3-Dimethyl-8-[2-(4-trifluoromethyl-phenyl)-ethyl]-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine | HCID 66734231 | — |
Reaction Steps
Prepared according to the previously described general procedure (GP11) by reaction of 2-(2,4-dimethyl-imidazol-1-yl)-ethylamine with 3-(4-trifluoromethyl-phenyl)-propionaldehyde. LC-MS: tR=0.64 min.; [M+H]+=324 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188082B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-9ce464119e7f48d29b9916d96e80243c |
| Source note | uspto-grants-2012_05 |