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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929678Generated: November 3, 2026

2-(2,4-Dimethyl-1H-imidazol-1-yl)ethanamine → 8-[2-(2,3-Dimethylphenyl)ethyl]-1,3-dimethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine

https://huagongshe.com/reaction/1929678

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2,4-Dimethyl-1H-imidazol-1-yl)ethanamineHCID 18460700—
Reactant3-(2,3-Dimethylphenyl)propanalHCID 21989629—
Product8-[2-(2,3-Dimethylphenyl)ethyl]-1,3-dimethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazineHCID 66733962—

Reaction Steps

Prepared according to the previously described general procedure (GP11) by reaction of 2-(2,4-dimethyl-imidazol-1-yl)-ethylamine with 3-(2,3-dimethyl-phenyl)-propionaldehyde. LC-MS: tR=0.61 min.; [M+H]+=284 g/mol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188082B2
Source datasetuspto-grants-2012_05
ORD IDord-179dff81f2434ed6a298d00c0f7b5ddb
Source noteuspto-grants-2012_05