3-[4-(Trifluoromethyl)phenyl]propanal → HCID 66733729, compound

HRID 1929684Notes

Reaction equation

HRID 1929684 reaction equation
[CH2:1]([C:3]1[N:4]([CH2:9][CH2:10][NH2:11])[CH:5]=[C:6]([CH3:8])[N:7]=1)[CH3:2].[F:12][C:13]([F:25])([F:24])[C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][CH:22]=O)=[CH:16][CH:15]=1>>[CH2:1]([C:3]1[N:4]2[CH2:9][CH2:10][NH:11][CH:22]([CH2:21][CH2:20][C:17]3[CH:18]=[CH:19][C:14]([C:13]([F:12])([F:24])[F:25])=[CH:15][CH:16]=3)[C:5]2=[C:6]([CH3:8])[N:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 216838073-[4-(Trifluoromethyl)phenyl]propanalHCID 66734117HCID 66734117, compound

Product 1

HCID 66733729HCID 66733729, compound

Procedure

Prepared according to the previously described general procedure (GP11) by reaction of 2-(2-ethyl-4-methyl-imidazol-1-yl)-ethylamine with 3-(4-trifluoromethyl-phenyl)-propionaldehyde. LC-MS: tR=0.65 min.; [M+H]+=338 g/mol.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-ad4edb2032f74ced8ba83a124fd49078
Source dataset
uspto-grants-2012_05
Patent number
US08188082B2

Reaction notes

Loading…