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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929769Generated: November 3, 2026

Tert-butyl propionylcarbamate → [(1S,4R)-4-(2,6-Dichloro-purin-9-yl)-cyclopent-2-enyl]-propionyl-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/1929769

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl propionylcarbamateHCID 14221819—
ReactantDi-Boc-[(1S,4R)-4-(2,6-dichloro-purin-9-yl)-cyclopent-2-enyl]-amineHCID 58025018—
Product[(1S,4R)-4-(2,6-Dichloro-purin-9-yl)-cyclopent-2-enyl]-propionyl-carbamic acid tert-butyl esterHCID 86622633—

Reaction Steps

The title compound is prepared analogously to di-Boc-[(1S,4R)-4-(2,6-dichloro-purin-9-yl)-cyclopent-2-enyl]-amine (by replacing di-t-butyliminodicarboxylate with propionyl-carbamic acid tert-butyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188100B2
Source datasetuspto-grants-2012_05
ORD IDord-f09b24bc4b864f949154268a1133b715
Source noteuspto-grants-2012_05