Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929846Generated: November 2, 2026

4-Chlorophenylboronic acid → HCID 24856673, compound

https://huagongshe.com/reaction/1929846

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorophenylboronic acidHCID 74299—
Reactant(-)-2-ButanolHCID 84682—
Reactant(1R,2R)-2-AminocyclohexanolHCID 735777—
ReactantMethyl 5-bromo-6-chloronicotinateHCID 2764313—
ProductHCID 24856673HCID 24856673—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 5, using 5-bromo-6-chloro-3-pyridinecarboxylic acid methyl ester, 4-chlorophenyl-boronic acid (commercially available), (R)-(−)-2-butanol (commercially available), and (1R,2R)-2-amino-cyclohexanol (commercially available) as starting materials. MS (ISP): 403.5 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188093B2
Source datasetuspto-grants-2012_05
ORD IDord-78135e026f2c4dadb16846a5ac98b361
Source noteuspto-grants-2012_05