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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929872Generated: November 2, 2026

N-Methylpropylamine → HCID 11950234, compound

https://huagongshe.com/reaction/1929872

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylpropylamineHCID 12315—
Reactant4-Fluorophenylboronic acidHCID 285645—
Reactant(1R,2R)-2-AminocyclohexanolHCID 735777—
ReactantMethyl 5-bromo-6-chloronicotinateHCID 2764313—
ProductHCID 11950234HCID 11950234—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 43, using 5-bromo-6-chloro-nicotinic acid methyl ester, N-methyl-N-propylamine (commercially available), 4-fluorophenyl-boronic acid (commercially available) and (1R,2R)-2-amino-cyclohexanol (commercially available) as starting materials. MS (ISP): 386.2 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188093B2
Source datasetuspto-grants-2012_05
ORD IDord-04363da9c48f435c9aa3fc9448faf918
Source noteuspto-grants-2012_05