HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,2-Trifluoroethanol → HCID 67504968, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,2-Trifluoroethanol | HCID 6409 | — |
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Reactant | (1R,2R)-2-Aminocyclohexanol | HCID 735777 | — |
| Reactant | Ethyl 5-bromo-6-chloro-2-methyl-3-pyridinecarboxylate | HCID 86619573 | — |
| Product | HCID 67504968 | HCID 67504968 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 114, using 5-bromo-6-chloro-2-methyl-3-pyridinecarboxylic acid ethyl ester, 2,2,2-trifluoroethanol, ((1R,2R)-2-amino-1-cyclohexanol and (4-chloro-phenyl)-boronic acid as starting materials to yield the product as off-white solid, MS (ISP) 443.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188093B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-c32e58047ba54073b20ba14b6b9104b9 |
| Source note | uspto-grants-2012_05 |