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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929916Generated: October 31, 2026

Pyrrolidine → HCID 67505173, compound

https://huagongshe.com/reaction/1929916

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
ReactantL-LeucinolHCID 111307—
Reactant(4-Methoxyphenyl)boronic acidHCID 201262—
ReactantMethyl 5-bromo-6-chloronicotinateHCID 2764313—
ProductHCID 67505173HCID 67505173—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 43, using 5-bromo-6-chloro-nicotinic acid methyl ester, pyrrolidine (commercially available), 4-methoxyphenyl-boronic acid (commercially available) and (S)-(+)-leucinol (commercially available) as starting materials. MS (ISP): 398.2 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188093B2
Source datasetuspto-grants-2012_05
ORD IDord-49bcc77c60b74f97b6ea88ee45493d71
Source noteuspto-grants-2012_05