HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethynylpyridine → HCID 24797710, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethynylpyridine | HCID 137268 | — |
| Reactant | (2R)-1-amino-2-cyclopropyl-propan-2-ol | HCID 51684102 | — |
| Reactant | HCID 73013037 | HCID 73013037 | — |
| Product | HCID 24797710 | HCID 24797710 | — |
Reaction Steps
The title compound was synthesized in analogy to the procedure described for the preparation of Example 140, using 2-ethynyl-pyridine (CAN 1945-84-2), 6-chloro-5-(4-chloro-phenyl)-nicotinic acid methyl ester, and (R)-α-(aminomethyl)-α-methyl-cyclopropanemethanol as starting materials, LC at 215 nm; Rt 3.16: 88%, m/z (ES+): 436.4 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188093B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-0ff480d33b324b0c8d28c25a590eebec |
| Source note | uspto-grants-2012_05 |