1,5-Pentanediol → HCID 67504913, compound

HRID 1929938Notes

Reaction equation

HRID 1929938 reaction equation
[Br:1][C:2]1[C:3](Cl)=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].[CH2:12]([OH:18])[CH2:13][CH2:14][CH2:15][CH2:16][OH:17]>>[Br:1][C:2]1[C:3]([O:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][OH:18])=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8]

Participants

3

Reactant 2

HCID 81051,5-PentanediolHCID 2854335-Bromo-6-chloropyridine-3-carboxylic acid

Product 1

HCID 67504913HCID 67504913, compound

Procedure

The title compound was synthesized in analogy to the procedure described for the preparation of Example 31a, using 5-bromo-6-chloro-nicotinic acid and 1,5-pentanediol as starting materials to give the product as brownish oil, MS (ISP): 302.3 (M−H+).

Workup

  1. customdescribed for the preparation of Example 31a

Sources & evidence

ORD record
ord-0d062a973fc842e3817e2c3b8411838f
Source dataset
uspto-grants-2012_05
Patent number
US08188093B2

Reaction notes

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