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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929945Generated: October 30, 2026

Pyrrolidine → HCID 24857434, compound

https://huagongshe.com/reaction/1929945

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
ReactantL-LeucinolHCID 111307—
Reactant3,4-Dichlorobenzeneboronic acidHCID 2734330—
ReactantMethyl 5-bromo-6-chloronicotinateHCID 2764313—
ProductHCID 24857434HCID 24857434—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 43, using 5-bromo-6-chloro-nicotinic acid methyl ester, pyrrolidine (commercially available), 3,4-dichlorophenyl-boronic acid (commercially available) and (S)-(+)-leucinol (commercially available) as starting materials. MS (ISP): 436.3 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188093B2
Source datasetuspto-grants-2012_05
ORD IDord-30f62fb9304246f1973f44f9b0868193
Source noteuspto-grants-2012_05