HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 24857435, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | L-Leucinol | HCID 111307 | — |
| Reactant | Methyl 5-bromo-6-chloronicotinate | HCID 2764313 | — |
| Reactant | (4-Chloro-3-methylphenyl)boronic acid | HCID 3786632 | — |
| Product | HCID 24857435 | HCID 24857435 | — |
Reaction Steps
The title compound was synthesized in analogy to the procedure described for the preparation of Example 43, using 5-bromo-6-chloro-nicotinic acid methyl ester, pyrrolidine (commercially available), 4-chloro-3-methylphenyl-boronic acid (commercially available) and (S)-(+)-leucinol (commercially available) as starting materials. MS (ISP): 416.3 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188093B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-f7f5b368909149e49c5114f9810d450f |
| Source note | uspto-grants-2012_05 |