HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 24857073, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 4-Fluorophenylboronic acid | HCID 285645 | — |
| Reactant | D(-)-Leucinol | HCID 2724002 | — |
| Reactant | Methyl 5-bromo-6-chloronicotinate | HCID 2764313 | — |
| Product | HCID 24857073 | HCID 24857073 | — |
Reaction Steps
The title compound was synthesized in analogy to the procedure described for the preparation of Example 43, using 5-bromo-6-chloro-nicotinic acid methyl ester, pyrrolidine (commercially available), 4-fluorophenyl-boronic acid (commercially available) and (R)-(−)-leucinol (commercially available) as starting materials. MS (ISP): 386.4 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188093B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-b10b2f2e3e8741c88753b532ec17f81c |
| Source note | uspto-grants-2012_05 |