2,2-Difluoro-2-phenylacetic acid → HCID 21957235, compound

HRID 193007Notes

Reaction equation

HRID 193007 reaction equation
[F:1][C:2]([C:3](=[O:4])[OH:5])([c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1)[F:12].[NH2:13][CH2:14][CH2:15][CH2:16][N:17]1[CH2:18][CH2:19][CH:20]([c:23]2[cH:24][c:25]([NH:30][C:31]([CH:32]([CH3:33])[CH3:34])=[O:35])[cH:26][cH:27][c:28]2[F:29])[CH2:21][CH2:22]1>>[F:1][C:2]([C:3](=[O:5])[NH:13][CH2:14][CH2:15][CH2:16][N:17]1[CH2:18][CH2:19][CH:20]([c:23]2[cH:24][c:25]([NH:30][C:31]([CH:32]([CH3:33])[CH3:34])=[O:35])[cH:26][cH:27][c:28]2[F:29])[CH2:21][CH2:22]1)([c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1)[F:12]

Participants

3

Reactant 2

HCID 7261532,2-Difluoro-2-phenylacetic acidHCID 21957238N-{3-[1-(3-aminopropyl)-4-piperidinyl]4-fluorophenyl}-2-methylpropanamide

Product 1

HCID 21957235HCID 21957235, compound

Sources & evidence

ORD record
ord-d2e9465df3384ed788e32e3ceafef6b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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