Hydrazine → HCID 57929856, compound

Participants

Reaction Conditions

Reaction Steps

A round bottomed flask was charged with 6-(2,4-difluorophenyl)-5-(2-(methylsulfinyl)pyrimidin-5-yl)imidazo[2,1-b]oxazole (0.16 g, 0.44 mmol), ACN (20 mL) and hydrazine (0.10 mL, 3.2 mmol). The reaction mixture was stirred at about 80° C. for about 2 h. The reaction mixture was concentrated to dryness and then triturated with Et2O to give the title compound (0.13 g, 89%). LC/MS (Table 1, Method o) Rt=2.56 min; MS m/z 329.1.

Provenance & Evidence