HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-4-fluorobenzaldehyde → 6-Fluoro-7-bromoisoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-4-fluorobenzaldehyde | HCID 173604 | — |
| Reactant | 6-Fluoroisoquinoline | HCID 21889847 | — |
| Product | 6-Fluoro-7-bromoisoquinoline | HCID 53402964 | — |
Reaction Steps
Starting from 3-bromo-4-fluoro-benzaldehyde, the title compound was prepared by the same reaction sequence as used for the synthesis of 6-fluoro-isoquinoline (3). Rt=0.91 min (Method B). Detected mass: 226.0/228.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188117B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-1bc020b3341d4c67a53539f92de595ec |
| Source note | uspto-grants-2012_05 |