HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydroxide, monohydrate → 4-Chlorobiphenyl-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | Ethyl 5-chloro-2-phenylbenzoate | HCID 59830347 | — |
| Product | 4-Chlorobiphenyl-2-carboxylic acid | HCID 21939858 | 80% |
Reaction Steps
Ethyl 5-chloro-2-phenylbenzoate (0.473 g, 1.81 mmol) was hydrolyzed with lithium hydroxide monohydrate to provide 5-chloro-2-phenylbenzoic acid (0.336 g, 80% yield). MS (ESI) m/z: 233.0 (M+H+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188113B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-7b753704064341a18ea3d30fc7089020 |
| Source note | uspto-grants-2012_05 |