4-Formylphenylboronic Acid → HCID 23160964, compound

HRID 1930499Notes

Reaction equation

HRID 1930499 reaction equation
Br[C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]2[O:12][C:11]([CH:13]=[O:14])=[CH:10][CH:9]=2)[CH:3]=1.[CH:15]([C:17]1[CH:22]=[CH:21][C:20](B(O)O)=[CH:19][CH:18]=1)=[O:16]>>[CH:15]([C:17]1[CH:22]=[CH:21][C:20]([C:7]2[CH:2]=[CH:3][C:4]([C:8]3[O:12][C:11]([CH:13]=[O:14])=[CH:10][CH:9]=3)=[N:5][CH:6]=2)=[CH:19][CH:18]=1)=[O:16]

Participants

3

Reactant 2

HCID 5910734-Formylphenylboronic AcidHCID 23160955HCID 23160955, compound

Product 1

HCID 23160964HCID 23160964, compoundYield 91%

Procedure

The same procedure described for 12 was used by employing compound 41 (1 equiv.) and 4-formylphenyl boronic acid (1 equiv.). Yield 91%, mp 217-219° C. 1H NMR (DMSO-d6); δ 7.46 (d, J=3.6 Hz, 1H), 7.71 (d, J=3.6 Hz, 1H), 8.03-8.05 (m, 5H), 8.37 (dd, J=1.8, 8.4 Hz, 1H), 9.11 (d, J=1.8 Hz, 1H), 9.69 (s, 1H), 10.07 (s, 1H). Anal. Calc. for C17H11NO3: C %, 73.63; H %, 3.99. Found C %, 73.51; H %, 4.23.

Sources & evidence

ORD record
ord-86316bf3ea5849238e1641fb0d1fc22b
Source dataset
uspto-grants-2012_05
Patent number
US08188121B2

Reaction notes

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