4-Cyanophenylboronic acid → HCID 12207760, compound

HRID 1930501Notes

Reaction equation

HRID 1930501 reaction equation
Br[C:2]1[CH:7]=[N:6][C:5](Br)=[CH:4][N:3]=1.[C:9]([C:11]1[CH:16]=[CH:15][C:14](B(O)O)=[CH:13][CH:12]=1)#[N:10]>>[C:9]([C:11]1[CH:16]=[CH:15][C:14]([C:2]2[CH:7]=[N:6][C:5]([C:14]3[CH:15]=[CH:16][C:11]([C:9]#[N:10])=[CH:12][CH:13]=3)=[CH:4][N:3]=2)=[CH:13][CH:12]=1)#[N:10]

Participants

3

Reactant 2

HCID 27343264-Cyanophenylboronic acidHCID 114704212,5-dibromopyrazine

Product 1

HCID 12207760HCID 12207760, compoundYield 52%

Procedure

The same procedure described for 1,4-Bis-(2′-cyanopyridin-5′-yl)phenylene was used by employing 2,5-dibromopyrazine and 4-cyanophenylboronic acid to furnish 74 in 52% yield; mp >300° C. (DMF). 1H NMR (DMSO-d6): δ 7.99 (d, J=8.4 Hz, 4H), 8.39 (d, J=8.4 Hz, 4H), 9.42 (s, 2H).

Sources & evidence

ORD record
ord-5f5563d8b4fb4558982181ec9be37e9b
Source dataset
uspto-grants-2012_05
Patent number
US08188121B2

Reaction notes

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