HCID 86652384, compound → HCID 66719501, compound

HRID 1930513Notes

Reaction equation

HRID 1930513 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2([C:23]([F:26])([F:25])[F:24])[CH2:13][CH2:12][N:11]([C:14]3[CH:22]=[CH:21][C:17]([C:18](Cl)=[O:19])=[CH:16][CH:15]=3)[CH2:10]2)[CH:5]=[C:6]([Cl:8])[CH:7]=1.ClC1C=C(C2(C(F)(F)F)CCN(C3C=CC(C(Cl)=[O:45])=C([N+]([O-])=O)C=3)C2)C=C(Cl)C=1.FC(F)(F)C1C=C(C2(C(F)(F)F)CCN(C3C=CC(C(Cl)=O)=C([N+]([O-])=O)C=3)C2)C=C(C(F)(F)F)C=1>>[Cl:8][C:6]1[CH:5]=[C:4]([C:9]2([C:23]([F:25])([F:26])[F:24])[CH2:13][CH2:12][N:11]([C:14]3[CH:15]=[CH:16][C:17]([C:18]([OH:19])=[O:45])=[CH:21][CH:22]=3)[CH2:10]2)[CH:3]=[C:2]([Cl:1])[CH:7]=1

Participants

4

Reactant 3

HCID 86652384HCID 86652384, compoundHCID 86652385HCID 86652385, compoundHCID 86652386HCID 86652386, compound

Product 1

HCID 66719501HCID 66719501, compound

Procedure

Representative compounds of the formula (V) and formula (V-a), respectively, include: 4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]benzoyl chloride; 4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-2-nitrobenzoyl chloride; 4-{3-[3,5-bis(trifluoromethyl)phenyl]-3-(trifluoromethyl)pyrrolidin-1-yl}-2-nitrobenzoyl chloride and the like.

Sources & evidence

ORD record
ord-ce80979b5c434bd8b2a248d8734d2764
Source dataset
uspto-grants-2012_05
Patent number
US08188122B2

Reaction notes

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