HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrimidine → 4-Benzyl-N-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrimidine | HCID 9260 | — |
| Reactant | 3-(2-phenylacetyl)dihydro-2H-pyran-4(3H)-one | HCID 59333779 | — |
| Reactant | HCID 178493227 | HCID 178493227 | — |
| Product | 4-Benzyl-N-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-amine | HCID 46198822 | 3.7% |
Reaction Steps
4-Benzyl-N-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-amine (16.00 mg, 3.7%) was obtained from 3-(2-phenylacetyl)dihydro-2H-pyran-4(3H)-one and 1-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)guanidine by the general procedure for pyrimidine preparation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188101B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-a6d07b3898374c1cb0927d74bd90a4b9 |
| Source note | uspto-grants-2012_05 |