Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(2-phenylacetyl)dihydro-2H-pyran-4(3H)-one → HCID 46198824, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(2-phenylacetyl)dihydro-2H-pyran-4(3H)-one | HCID 59333779 | — |
| 반응물 | HCID 178432900 | HCID 178432900 | — |
| 생성물 | HCID 46198824 | HCID 46198824 | 11.5% |
반응 단계
4-Benzyl-N-(4-(2-methyl-1H-imidazol-1-yl)phenyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-amine (42.0 mg, 11.5%) was obtained from 1-(4-(2-methyl-1H-imidazol-1-yl)phenyl)guanidine and 3-(2-phenylacetyl)dihydro-2H-pyran-4(3H)-one by general procedure for the preparation of pyrimidines. The crude product was purified by preparative HPLC twice. Purification using ammoniumacetate buffer was followed by purification using a 0.1% TFA. MS (ES+) m/z 398.1 (M+H)+
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08188101B2 |
| 출처 데이터셋 | uspto-grants-2012_05 |
| ORD ID | ord-3a71157e854743ebaa3ecadc19c9d5c4 |
| 출처 메모 | uspto-grants-2012_05 |