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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1930614Generated: October 30, 2026

Formaldehyde → HCID 46199108, compound

https://huagongshe.com/reaction/1930614

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantHCID 59333804HCID 59333804—
ProductHCID 46199108HCID 4619910810.4%

Reaction Steps

4-(2-Cyclohexylethyl)-6-methyl-N-(4-(2-methyl-1H-imidazol-1-yl)phenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine (20.0 mg, 10.4%) was synthesised from 4-(2-cyclohexylethyl)-N-(4-(2-methyl-1H-imidazol-1-yl)phenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine and formaldehyde according to the general procedure for reductive amination. MS (ES+) m/z 431.4 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188101B2
Source datasetuspto-grants-2012_05
ORD IDord-5ab93ce7770749ecb54180cb7bc89f57
Source noteuspto-grants-2012_05