HRID1930619

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID756

Acetaldehyde, hydroxy-

C2H4O2

结构：COc1cccc(Cc2nc(Nc3ccc(-n4ccnc4C)cc3)nc3c2CNCC3)c1

HCID59333786

未命名化合物

PRODUCTS

生成物

结构：COc1cccc(Cc2nc(Nc3ccc(-n4ccnc4C)cc3)nc3c2CN(CCO)CC3)c1

HCID46199111

未命名化合物

收率 13%

PROCEDURE

实验过程

2-(4-(3-Methoxybenzyl)-2-(4-(2-methyl-1H-imidazol-1-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)ethanol (19.6 mg, 13%) was synthesised from 4-(3-methoxybenzyl)-N-(4-(2-methyl-1H-imidazol-1-yl)phenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine (Example 53a) and glycolaldehyde according to the general procedure for reductive amination. MS (ES+) m/z 471.3 (M+H)+