反应详情

1-(4-(Cyclohexyl(methyl)amino)-2-(4-(oxazol-5-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)ethanone (12.6 mg, 17%) was prepared from N-methylcyclohexanamine and 6-acetyl-2-(4-(oxazol-5-yl)phenylamino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl trifluoromethanesulfonate according to the general procedure for amine substitution of tosylate on pyrimidines.