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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1930813Generated: October 30, 2026

Hydrochloric Acid → 5-Pyrrolidin-1-yl-2,3-dihydro-1H-isoindole

https://huagongshe.com/reaction/1930813

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-Pyrrolidin-1-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753484—
Product5-Pyrrolidin-1-yl-2,3-dihydro-1H-isoindoleHCID 57753397—

Reaction Steps

Prepared in analogy to Example A3 (e) from 5-Pyrrolidin-1-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and HCl. Brown oil. MS (m/e): 189.6 (M+H+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188139B2
Source datasetuspto-grants-2012_05
ORD IDord-4bd9e000f8474dfcba2675e04a9fd026
Source noteuspto-grants-2012_05