HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → (2-Fluoro-6-hydroxymethyl-4-trifluoromethyl-phenyl)-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 3-Fluoro-N,N-diisopropyl-5-trifluoromethyl-benzamide | HCID 44203143 | — |
| Reactant | 4-Fluoro-6-trifluoromethyl-3H-isobenzofuran-1-one | HCID 57753255 | — |
| Product | (2-Fluoro-6-hydroxymethyl-4-trifluoromethyl-phenyl)-methanol | HCID 57753663 | — |
Reaction Steps
Prepared in analogy to Example A16 (a) from 4-Fluoro-6-trifluoromethyl-3H-isobenzofuran-1-one e and sodium borohydride. Colorless oil. MS (m/e): 225.1 ([M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188139B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-ba4200ef43c74c74aba42a094efa8463 |
| Source note | uspto-grants-2012_05 |