HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-(5-Methyl-thiazol-2-yl)-2,3-dihydro-1H-isoindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-(5-Methyl-thiazol-2-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester | HCID 57753262 | — |
| Product | 5-(5-Methyl-thiazol-2-yl)-2,3-dihydro-1H-isoindole | HCID 57753629 | — |
Reaction Steps
Prepared in analogy to Example A3(e) from 5-(5-Methyl-thiazol-2-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and using trifluoacetic acid instead of hydrochloride acid. Brown gum. MS (m/e): 217.0 ([M+H]+, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188139B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-50a8e7c5241245ab91aab74889b001b2 |
| Source note | uspto-grants-2012_05 |