Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1930863Generated: November 1, 2026

Ethanol → 5-Ethoxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1930863

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactanttert-Butyl 5-iodoisoindoline-2-carboxylateHCID 57753580—
Product5-Ethoxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753260—

Reaction Steps

Prepared in analogy to Example A6(a) from 5-iodo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester (Example A38(b)) and ethanol. Light brown solid. MS (m/e): 208.1 ([M+H-Me2C═CH2]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188139B2
Source datasetuspto-grants-2012_05
ORD IDord-121a077ce12246c78d1a0b5ab54c4c03
Source noteuspto-grants-2012_05