HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Oxotetrahydrofuran → 3-(2-Benzyl-2,3-Dihydro-1H-isoindol-5-yl)-tetrahydro-furan-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Oxotetrahydrofuran | HCID 529392 | — |
| Reactant | 2-Benzyl-5-bromoisoindoline | HCID 53416550 | — |
| Product | 3-(2-Benzyl-2,3-Dihydro-1H-isoindol-5-yl)-tetrahydro-furan-3-ol | HCID 57753389 | — |
Reaction Steps
Prepared in analogy to Example A62(b) from 2-benzyl-5-bromo-2,3-dihydro-1H-isoindole (Example A62(a)) and tetrahydrofuran-3-one. Brown oil. MS (m/e): 296.4 ([M+H]+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188139B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-6676f163134943a0ae733710ec626cee |
| Source note | uspto-grants-2012_05 |