HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 5-Chloro-6-(tetrahydro-furan-3-yl)-2,3-Dihydro-1H-isoindole trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 5-Chloro-6-(tetrahydro-furan-3-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester | HCID 57753320 | — |
| Product | 5-Chloro-6-(tetrahydro-furan-3-yl)-2,3-Dihydro-1H-isoindole trifluoroacetate | HCID 68821451 | — |
Reaction Steps
Prepared in analogy to Example A2(c) from 5-chloro-6-(tetrahydro-furan-3-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and trifluoroacetic acid. Brown oil. MS (m/e): 226.2 ([{37Cl}M+H]+, 33%), 224.2 ([{35Cl}M+H]+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188139B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-ae9d57c6d0f7497f8dd5d236bad4367f |
| Source note | uspto-grants-2012_05 |