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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1930960Generated: November 2, 2026

Trifluoroacetic acid → 5-Cyclopropylmethoxy-2,3-dihydro-1H-isoindole trifluoroacetate

https://huagongshe.com/reaction/1930960

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant5-Cyclopropylmethoxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753275—
Product5-Cyclopropylmethoxy-2,3-dihydro-1H-isoindole trifluoroacetateHCID 68825599—

Reaction Steps

Prepared in analogy to Example A2(c) from 5-cyclopropylmethoxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and trifluoroacetic acid. Yellow oil. MS (m/e): 190.4 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188139B2
Source datasetuspto-grants-2012_05
ORD IDord-80b40947668741b1b281578dff8eec4b
Source noteuspto-grants-2012_05