HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,2-Trifluoroethanol → 5-Methanesulfonyl-2-(2,2,2-trifluoro-ethoxy)-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,2-Trifluoroethanol | HCID 6409 | — |
| Reactant | 2-Chloro-5-(methylsulphonyl)benzoic acid | HCID 2329132 | — |
| Product | 5-Methanesulfonyl-2-(2,2,2-trifluoro-ethoxy)-benzoic acid | HCID 21100312 | — |
Reaction Steps
Prepared in analogy to Example B1 (b) from 2-chloro-5-methanesulfonyl-benzoic acid (Example B1(a)) and 2,2,2-trifluoro-ethanol. The crude material was purified by preparative HPLC to yield the title compound as a white solid. MS (m/e): 297.0 ([M−H]−, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188139B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-2deb99b06dc14b85b346891165488000 |
| Source note | uspto-grants-2012_05 |