Tritylamine → 4-Iodo-2-trityl-2,3-dihydro-1H-isoindole

HRID 1931015Notes

Reaction equation

HRID 1931015 reaction equation
Br[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([I:9])[C:4]=1[CH2:10]Br.[C:12]1([C:18]([NH2:31])([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[I:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]2[C:4]=1[CH2:10][N:31]([C:18]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)([C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1)[CH2:2]2

Participants

3

Reactant 2

HCID 138598TritylamineHCID 577535081,2-Bis-bromomethyl-3-iodo-benzene

Product 1

HCID 577534134-Iodo-2-trityl-2,3-dihydro-1H-isoindole

Procedure

Prepared in analogy to Example A2 (b) from 1,2-Bis-bromomethyl-3-iodo-benzene and triphenylmethylamine. White solid.

Sources & evidence

ORD record
ord-85e48c1658814eda83a2fc10f39f447d
Source dataset
uspto-grants-2012_05
Patent number
US08188139B2

Reaction notes

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