HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Tri-n-butylstannyl)pyridine → [5-Methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-(2-pyridin-4-yl-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Tri-n-butylstannyl)pyridine | HCID 2737318 | — |
| Reactant | (2-Chloro-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone | HCID 57753234 | — |
| Product | [5-Methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-(2-pyridin-4-yl-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-methanone | HCID 57753679 | — |
Reaction Steps
Prepared in analogy to Example A54(a) from (2-chloro-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone (Example C4) and 4-tributylstannanylpyridine. White solid. MS (m/e): 492.1 [M+H]+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188139B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-eba1a840f2ac435285783e121c7e86ab |
| Source note | uspto-grants-2012_05 |