Sodium borohydride → HCID 24742696, compound

HRID 1931032Notes

Reaction equation

[CH3:1][C:2]1[CH:14]=[C:13]([CH2:15][CH2:16][C:17]([C:19]2[CH:24]=[CH:23][C:22]([O:25][C:26]([F:29])([F:28])[F:27])=[CH:21][CH:20]=2)=[O:18])[CH:12]=[C:11]([CH3:30])[C:3]=1[O:4][C:5]([CH3:10])([CH3:9])[C:6]([OH:8])=[O:7].[BH4-].[Na+]>>[OH:18][CH:17]([C:19]1[CH:24]=[CH:23][C:22]([O:25][C:26]([F:27])([F:28])[F:29])=[CH:21][CH:20]=1)[CH2:16][CH2:15][C:13]1[CH:14]=[C:2]([CH3:1])[C:3]([O:4][C:5]([CH3:10])([CH3:9])[C:6]([OH:8])=[O:7])=[C:11]([CH3:30])[CH:12]=1

Participants

Reactant 2

HCID 4311764Sodium borohydride

HCID 24742348HCID 24742348, compound

Product 1

HCID 24742696HCID 24742696, compound

Procedure

This compound was prepared following the general procedure D, using 2-[2,6-dimethyl-4-[3-[4-(trifluoromethyloxy)phenyl]-3-oxo-propyl]phenoxy]-2-methylpropanoic acid, and 4 equivalent amounts of sodium borohydride.

Workup

customThis compound was prepared

Sources & evidence

ORD record: ord-da999524a8e94051bf3b109c1e4b843a
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08188148B2

Reaction notes

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