Acetanilide → HCID 12798655, compound

Participants

Reaction Steps

Method A applied to 4-dimethoxymethyl-1-iodo-2-nitrobenzene (155 mg, 0.5 mmol) and N-phenylacetamide (81 mg, 0.6 mmol) yielded the title compound as pale yellow oil (79 mg, 67% yield). 1H NMR (DMSO) δ 2.50 (s, 3H), 7.31 (d, J=8.3Hz, 1H), 7.61-7.68 (m, 5H), 7.82 (d, J=8.3Hz, 1H), 8.25 (s, 1H), 10.10 (s, 1H); 13C NMR δ 13.6, 111.4, 120.1, 124.2, 127.0, 129.8, 130.2, 132.3, 139.1, 154.7, 158.3, 192.4. HRMS (FAB): cal. for C15H13N2O [M+H+]: 237.1028; found: 237.1024.

Provenance & Evidence