Benzanilide → 1,2-Diphenylbenzimidazole

Participants

Reaction Steps

Method A applied to 1-iodo-2-nitrobenzene (125 mg, 0.5 mmol) and benzanilide (118 mg, 0.6 mmol) yielded the title compound as pale yellow solid (112 mg, 83%). mp 105-107° C. 1H NMR (DMSO) δ 7.24 (d, J=7.9Hz, 1H), 7.35-7.62 (m, 12H), 7.84 (d, J=7.6Hz, 1H); 13C NMR δ 111.0, 118.1, 123.7, 124.1, 127.5, 127.9, 128.4, 129.2, 129.3, 130.0, 130.2, 135.5, 136.2, 139.3, 151.3. HRMS (FAB): cal. for C19H15N2 [M+H+]: 271.1235; found: 271.1230.

Provenance & Evidence