o-Iodonitrobenzene → HCID 24821366, compound

Participants

Reaction Steps

Method A applied to 1-iodo-2-nitrobenzene (125 mg, 0.5 mmol) and nicotinanilide (119 mg, 0.6 mmol) yielded the title compound as brown solid (68 mg, 50%). mp 110-112° C. 1H NMR (DMSO) δ 7.26 (d, J=7.3Hz, 1H), 7.32-7.63 (m, 8H), 7.86 (d, J=7.6 Hz, 1H), 7.89 (d, J=7.8Hz, 1H), 8.62 (d, J=3.0Hz, 1H), 8.72 (br s, 1H); 13C NMR δ 111.0, 118.7, 123.8, 124.0, 124.4, 125.4, 127.6, 129.5, 130.2, 135.2, 136.4, 137.7, 140.3, 148.6, 149.6, 158.3. HRMS (FAB): cal. for C18H14N3 [M+H+]: 272.1188; found: 272.1180.

Provenance & Evidence